Effects of Japanese herbal medicine inchin-ko-to on endotoxin-induced cholestasis in the rat
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Effects of Japanese herbal medicine Inchin-ko-to on endotoxin-induced cholestasis in the rat.
BACKGROUND/OBJECTIVE Inchin-ko-to (ICKT) is an herbal medicine used in Japan to treat jaundice and liver fibrosis.We investigated the effect of oral ICKT supplementation on endotoxin-induced cholestasis in the rat. MATERIAL AND METHODS Lipopolysaccharide (LPS) injection (1 mg/kg body weight i.p.) was used as a model of sepsis-induced cholestasis. Bile flow, biliary bile salt secretion, biliar...
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